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Inflammatory monocyte-derived dendritic cells mediate autoimmunity in murine model of systemic lupus erythematosus

Using a mouse model of systemic lupus erythematosus (SLE), we recently demonstrated that the two major manifestations of SLE are mechanistically independent because the type I IFN pathway leads to the autoantibody production whereas the NF-κB activation is sufficient for the development of glomerulo...

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Detalles Bibliográficos
Autores principales: Miyagawa, Fumi, Tagaya, Yutaka, Ozato, Keiko, Horie, Kyoji, Asada, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388367/
https://www.ncbi.nlm.nih.gov/pubmed/32743540
http://dx.doi.org/10.1016/j.jtauto.2020.100060