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Decreased HLA-DQ expression on peripheral blood cells in children with varying number of beta cell autoantibodies

The risk for type 1 diabetes is strongly associated with HLA-DQ and the appearance of beta cell autoantibodies against either insulin, glutamate decarboxylase (GAD65), insulinoma-associated protein-2 (IA-2), or zinc transporter 8 (ZnT8). Prolonged exposure to autoantibodies may be related to T cell...

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Detalles Bibliográficos
Autores principales: Andersson Svärd, Agnes, Maziarz, Marlena, Ramelius, Anita, Lundgren, Markus, Lernmark, Åke, Elding Larsson, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388396/
https://www.ncbi.nlm.nih.gov/pubmed/32743532
http://dx.doi.org/10.1016/j.jtauto.2020.100052