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Selective inhibition of PI3K110α as a novel therapeutic strategy for cetuximab-resistant oral squamous cell carcinoma

High expression of the 110 kDa catalytic subunit of the class IA PI3K (PI3Kp110α) may play an important role in cetuximab resistance exhibited by both colorectal cancer and head and neck squamous cell carcinoma. Therefore, the present study aimed to examine the association between the expression of...

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Detalles Bibliográficos
Autores principales: Tsuchihashi, Hiroki, Naruse, Tomofumi, Yanamoto, Souichi, Okuyama, Kohei, Furukawa, Kohei, Omori, Keisuke, Umeda, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388413/
https://www.ncbi.nlm.nih.gov/pubmed/32705230
http://dx.doi.org/10.3892/or.2020.7674