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Paxillin knockdown suppresses metastasis and epithelial-mesenchymal transition in colorectal cancer via the ERK signalling pathway

Paxillin (PXN) is a cytoplasmic protein that plays an important role in regulating focal adhesion, cytoskeletal rearrangements and cell motility. The present study aimed to investigate the role of PXN in the metastasis of human colorectal cancer (CRC) and its possible mechanisms. Immunohistochemical...

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Detalles Bibliográficos
Autores principales: Wen, Long, Zhang, Xiaoqian, Zhang, Junling, Chen, Shanwen, Ma, Yongchen, Hu, Jianwen, Yue, Taohua, Wang, Jingui, Zhu, Jing, Wu, Tao, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388420/
https://www.ncbi.nlm.nih.gov/pubmed/32705241
http://dx.doi.org/10.3892/or.2020.7687