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Trp53 regulates platelets in bone marrow via the PI3K pathway

The p53 gene is well known as a key tumor suppressor gene; it is vital for hematopoietic stem cell differentiation and growth. In the present study, the change of platelets (PLTs) in p53 knockout mice (p53(-/-) mice) was investigated. The peripheral blood cell subsets and PLT parameters in p53(-/-)m...

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Detalles Bibliográficos
Autores principales: Yang, Mingming, Liu, Qing, Niu, Ting, Kuang, Jianbiao, Zhang, Xiaohan, Jiang, Lingbi, Li, Siqi, He, Xiaodong, Wang, Lijing, Li, Jiangchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388439/
https://www.ncbi.nlm.nih.gov/pubmed/32765666
http://dx.doi.org/10.3892/etm.2020.8850