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Trp53 regulates platelets in bone marrow via the PI3K pathway
The p53 gene is well known as a key tumor suppressor gene; it is vital for hematopoietic stem cell differentiation and growth. In the present study, the change of platelets (PLTs) in p53 knockout mice (p53(-/-) mice) was investigated. The peripheral blood cell subsets and PLT parameters in p53(-/-)m...
Autores principales: | Yang, Mingming, Liu, Qing, Niu, Ting, Kuang, Jianbiao, Zhang, Xiaohan, Jiang, Lingbi, Li, Siqi, He, Xiaodong, Wang, Lijing, Li, Jiangchao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388439/ https://www.ncbi.nlm.nih.gov/pubmed/32765666 http://dx.doi.org/10.3892/etm.2020.8850 |
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