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Lipoxin A4 attenuates uric acid-activated, NADPH oxidase-dependent oxidative stress by interfering with translocation of p47phox in human umbilical vein endothelial cells

LipoxinA4 (LXA4) is a well-known key mediator of endogenous anti-inflammation and of the resolution of inflammation. Considerable oxidative stress occurs during inflammation due to the generation of reactive oxidative species (ROS). Moreover, high levels of uric acid (UA) contribute to endothelial c...

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Detalles Bibliográficos
Autores principales: Zhou, You, You, Hui, Zhang, Aijie, Jiang, Xingliang, Pu, Zheyan, Xu, Guoqiang, Zhao, Mingcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388524/
https://www.ncbi.nlm.nih.gov/pubmed/32765680
http://dx.doi.org/10.3892/etm.2020.8812