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Ginsenoside Rg1 protects against Sca-1(+) HSC/HPC cell aging by regulating the SIRT1-FOXO3 and SIRT3-SOD2 signaling pathways in a γ-ray irradiation-induced aging mice model

Aging is characterized by a progressive deterioration in metabolic functions. The present study aimed to investigate the antagonistic effects of ginsenoside Rg1 (Rg1) on the γ-ray irradiation-induced aging of mixed hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs). C57BL/6 mi...

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Detalles Bibliográficos
Autores principales: Tang, Yan-Long, Zhou, Yue, Wang, Ya-Ping, He, Ying-Hong, Ding, Ji-Chao, Li, Yuan, Wang, Cui-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388550/
https://www.ncbi.nlm.nih.gov/pubmed/32765665
http://dx.doi.org/10.3892/etm.2020.8810