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IGF-IR promotes clonal cell proliferation in myelodysplastic syndromes via inhibition of the MAPK pathway

Type 1 insulin-like growth factor receptor (IGF-IR) signaling is considered to serve a key role in the development of cancer. However, the effects of IGF-IR on the malignant characteristics of myelodysplastic syndrome (MDS) clonal cells remains to be determined. In the present study it was demonstra...

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Detalles Bibliográficos
Autores principales: He, Qi, Zheng, Qingqing, Xu, Feng, Shi, Wenhui, Guo, Juan, Zhang, Zheng, Zhao, Sida, Li, Xiao, Chang, Chunkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388562/
https://www.ncbi.nlm.nih.gov/pubmed/32583001
http://dx.doi.org/10.3892/or.2020.7652