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Accelerated Development of Rod Photoreceptors in Retinal Organoids Derived from Human Pluripotent Stem Cells by Supplementation with 9-cis Retinal

Human pluripotent stem cells (PSCs) can be differentiated into retinal organoids with proper neural layer organization, yet the protocols are technically challenging and time consuming. We have modified a widely used differentiation protocol by switching all-trans retinoic acid with 9-cis retinal to...

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Detalles Bibliográficos
Autores principales: Kelley, Ryan A., Chen, Holly Y., Swaroop, Anand, Li, Tiansen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388645/
https://www.ncbi.nlm.nih.gov/pubmed/32728670
http://dx.doi.org/10.1016/j.xpro.2020.100033