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Computational methods for predicting 3D genomic organization from high-resolution chromosome conformation capture data

The advent of high-resolution chromosome conformation capture assays (such as 5C, Hi-C and Pore-C) has allowed for unprecedented sequence-level investigations into the structure–function relationship of the genome. In order to comprehensively understand this relationship, computational tools are req...

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Detalles Bibliográficos
Autores principales: MacKay, Kimberly, Kusalik, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388788/
https://www.ncbi.nlm.nih.gov/pubmed/32353112
http://dx.doi.org/10.1093/bfgp/elaa004