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Doxorubicin-induced oxidative and nitrosative stress: Mitochondrial connexin 43 is at the crossroads
Oxidative stress is widely accepted as a key factor of doxorubicin (Doxo)-induced cardiotoxicity. There is evidence to indicate that nitrosative stress is involved in this process, and that Doxo interacts by amplifying cell damage. Mitochondrial connexin 43 (mitoCx43) can confer cardioprotective eff...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388829/ https://www.ncbi.nlm.nih.gov/pubmed/32705166 http://dx.doi.org/10.3892/ijmm.2020.4669 |