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Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis

The current chemotherapeutical treatment against alveolar echinococcosis relies exclusively on benzimidazoles, which are not parasiticidal and can induce severe toxicity. There are no alternative treatment options. To identify novel drugs with activity against Echinococcus multilocularis metacestode...

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Detalles Bibliográficos
Autores principales: Lundström-Stadelmann, Britta, Rufener, Reto, Hemphill, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389337/
https://www.ncbi.nlm.nih.gov/pubmed/32636148
http://dx.doi.org/10.1016/j.ijpddr.2020.06.002