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Firing activity of locus coeruleus noradrenergic neurons decreases in necdin-deficient mice, an animal model of Prader–Willi syndrome

BACKGROUND: Prader–Willi syndrome (PWS) is a neurodevelopmental disorder characterized by multiple respiratory, cognitive, endocrine, and behavioral symptoms, such as central apnea, intellectual disabilities, exaggerated stress responses, and temper tantrums. The locus coeruleus noradrenergic system...

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Detalles Bibliográficos
Autores principales: Wu, Rui-Ni, Hung, Wei-Chen, Chen, Ching-Tsuey, Tsai, Li-Ping, Lai, Wen-Sung, Min, Ming-Yuan, Wong, Shi-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389383/
https://www.ncbi.nlm.nih.gov/pubmed/32727346
http://dx.doi.org/10.1186/s11689-020-09323-4