NF-κB p65-dependent transcriptional regulation of histone deacetylase 2 contributes to the chronic constriction injury-induced neuropathic pain via the microRNA-183/TXNIP/NLRP3 axis

BACKGROUND: Neuropathic pain is related to the sustained activation of neuroglial cells and the production of proinflammatory cytokines in the spinal dorsal horn. However, the clinical efficacy of currently available treatments is very limited. The transcription factor nuclear factor κB (NF-κB) is a...

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Detalles Bibliográficos
Autores principales: Miao, Jiamin, Zhou, Xuelong, Ji, Tianjiao, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389436/
https://www.ncbi.nlm.nih.gov/pubmed/32723328
http://dx.doi.org/10.1186/s12974-020-01901-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389436/
https://www.ncbi.nlm.nih.gov/pubmed/32723328
http://dx.doi.org/10.1186/s12974-020-01901-6

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