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USP18 directly regulates Snail1 protein through ubiquitination pathway in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is one of the most common digestive malignant tumors in the world. Ubiquitin-specific peptidase 18 (USP18) plays a regulatory role in tumorigenesis, and abnormal expression of Snail1 is also believed to be related to tumorigenesis. However, whether USP18 could aff...

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Detalles Bibliográficos
Autores principales: Huang, Fakun, Zheng, Chengying, Huang, Longkai, Lin, Changqing, Wang, Jiaxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389447/
https://www.ncbi.nlm.nih.gov/pubmed/32742193
http://dx.doi.org/10.1186/s12935-020-01442-1