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Anti-tubercular derivatives of rhein require activation by the monoglyceride lipase Rv0183
The emergence and perseverance of drug resistant strains of Mycobacterium tuberculosis (Mtb) ensures that drug discovery efforts remain at the forefront of tuberculosis research. There are numerous different approaches that can be employed to lead to the discovery of anti-tubercular agents. In this...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389528/ https://www.ncbi.nlm.nih.gov/pubmed/32743152 http://dx.doi.org/10.1016/j.tcsw.2020.100040 |