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Intermittent parathyroid hormone (1–34) supplementation of bone marrow stromal cell cultures may inhibit hypertrophy, but at the expense of chondrogenesis

BACKGROUND: Bone marrow stromal cells (BMSC) have promise in cartilage tissue engineering, but for their potential to be fully realised, the propensity to undergo hypertrophy must be mitigated. The literature contains diverging reports on the effect of parathyroid hormone (PTH) on BMSC differentiati...

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Detalles Bibliográficos
Autores principales: Music, Ena, Futrega, Kathryn, Palmer, James S., Kinney, Mackenzie, Lott, Bill, Klein, Travis J., Doran, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389809/
https://www.ncbi.nlm.nih.gov/pubmed/32727579
http://dx.doi.org/10.1186/s13287-020-01820-6