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Intermittent parathyroid hormone (1–34) supplementation of bone marrow stromal cell cultures may inhibit hypertrophy, but at the expense of chondrogenesis
BACKGROUND: Bone marrow stromal cells (BMSC) have promise in cartilage tissue engineering, but for their potential to be fully realised, the propensity to undergo hypertrophy must be mitigated. The literature contains diverging reports on the effect of parathyroid hormone (PTH) on BMSC differentiati...
Autores principales: | Music, Ena, Futrega, Kathryn, Palmer, James S., Kinney, Mackenzie, Lott, Bill, Klein, Travis J., Doran, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389809/ https://www.ncbi.nlm.nih.gov/pubmed/32727579 http://dx.doi.org/10.1186/s13287-020-01820-6 |
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