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The molecular effect of a polymorphic microRNA binding site of Wolfram syndrome 1 gene in dogs

BACKGROUND: Although the molecular function of wolframin remains unclear, the lack of this protein is known to cause stress in the endoplasmic reticulum. Some variants in the Wolfram Syndrome 1 gene (WFS1) were associated with various neuropsychiatric disorders in humans, such as aggressiveness, imp...

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Detalles Bibliográficos
Autores principales: Koller, Dora, Kubinyi, Eniko, Elek, Zsuzsanna, Nemeth, Helga, Miklosi, Adam, Sasvari-Szekely, Maria, Ronai, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390163/
https://www.ncbi.nlm.nih.gov/pubmed/32723293
http://dx.doi.org/10.1186/s12863-020-00879-7