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The molecular effect of a polymorphic microRNA binding site of Wolfram syndrome 1 gene in dogs
BACKGROUND: Although the molecular function of wolframin remains unclear, the lack of this protein is known to cause stress in the endoplasmic reticulum. Some variants in the Wolfram Syndrome 1 gene (WFS1) were associated with various neuropsychiatric disorders in humans, such as aggressiveness, imp...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390163/ https://www.ncbi.nlm.nih.gov/pubmed/32723293 http://dx.doi.org/10.1186/s12863-020-00879-7 |