Estrogen receptor α phosphorylated at Ser216 confers inflammatory function to mouse microglia

BACKGROUND: Estrogen receptor α (ERα) has been suggested to regulate anti-inflammatory signaling in brain microglia, the only resident immune cells in the brain. ERα conserves the phosphorylation motif at Ser216 within the DNA binding domain. Previously, Ser216 was found to be phosphorylated in neut...

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Detalles Bibliográficos
Autores principales: Shindo, Sawako, Chen, Shih-Heng, Gotoh, Saki, Yokobori, Kosuke, Hu, Hao, Ray, Manas, Moore, Rick, Nagata, Kiyoshi, Martinez, Jennifer, Hong, Jau-Shyong, Negishi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390202/
https://www.ncbi.nlm.nih.gov/pubmed/32727504
http://dx.doi.org/10.1186/s12964-020-00578-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390202/
https://www.ncbi.nlm.nih.gov/pubmed/32727504
http://dx.doi.org/10.1186/s12964-020-00578-x

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