A mathematical model to quantify the effects of platelet count, shear rate, and injury size on the initiation of blood coagulation under venous flow conditions

Platelets upregulate the generation of thrombin and reinforce the fibrin clot which increases the incidence risk of venous thromboembolism (VTE). However, the role of platelets in the pathogenesis of venous cardiovascular diseases remains hard to quantify. An experimentally validated model of thromb...

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Detalles Bibliográficos
Autores principales: Bouchnita, Anass, Terekhov, Kirill, Nony, Patrice, Vassilevski, Yuri, Volpert, Vitaly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390270/
https://www.ncbi.nlm.nih.gov/pubmed/32726315
http://dx.doi.org/10.1371/journal.pone.0235392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390270/
https://www.ncbi.nlm.nih.gov/pubmed/32726315
http://dx.doi.org/10.1371/journal.pone.0235392

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