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An immunohistochemical prostate cell identification key indicates that aging shifts procollagen 1A1 production from myofibroblasts to fibroblasts in dogs prone to prostate-related urinary dysfunction

BACKGROUND: The identity and spatial distribution of prostatic cell types has been determined in humans but not in dogs, even though aging- and prostate-related voiding disorders are common in both species and mechanistic factors, such as prostatic collagen accumulation, appear to be shared between...

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Detalles Bibliográficos
Autores principales: Ruetten, Hannah, Cole, Clara, Wehber, Marlyse, Wegner, Kyle A., Girardi, Nicholas M., Peterson, Nelson T., Scharpf, Brandon R., Romero, Michael F., Wood, Michael W., Colopy, Sara A., Bjorling, Dale E., Vezina, Chad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390344/
https://www.ncbi.nlm.nih.gov/pubmed/32726309
http://dx.doi.org/10.1371/journal.pone.0232564