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Potential mechanisms of action of celastrol against rheumatoid arthritis: Transcriptomic and proteomic analysis

The clinical efficacy for treating of celastrol rheumatoid arthritis (RA) has been well-documented, but its mechanism of action remains unclear. Here we explored through what proteins and processes celastrol may act in activated fibroblast-like synoviocytes (FLS) from RA patients. Differential expre...

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Detalles Bibliográficos
Autores principales: Xinqiang, Song, Erqin, Dai, Yu, Zhang, Hongtao, Du, Lei, Wang, Ningning, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390347/
https://www.ncbi.nlm.nih.gov/pubmed/32726313
http://dx.doi.org/10.1371/journal.pone.0233814