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Potential mechanisms of action of celastrol against rheumatoid arthritis: Transcriptomic and proteomic analysis
The clinical efficacy for treating of celastrol rheumatoid arthritis (RA) has been well-documented, but its mechanism of action remains unclear. Here we explored through what proteins and processes celastrol may act in activated fibroblast-like synoviocytes (FLS) from RA patients. Differential expre...
Autores principales: | Xinqiang, Song, Erqin, Dai, Yu, Zhang, Hongtao, Du, Lei, Wang, Ningning, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390347/ https://www.ncbi.nlm.nih.gov/pubmed/32726313 http://dx.doi.org/10.1371/journal.pone.0233814 |
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