Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site

ADP-ribosylhydrolase-like 1 (Adprhl1) is a pseudoenzyme expressed in the developing heart myocardium of all vertebrates. In the amphibian Xenopus laevis, knockdown of the two cardiac Adprhl1 protein species (40 and 23 kDa) causes failure of chamber outgrowth but this has only been demonstrated using...

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Detalles Bibliográficos
Autores principales: Smith, Stuart J., Towers, Norma, Demetriou, Kim, Mohun, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390403/
https://www.ncbi.nlm.nih.gov/pubmed/32726316
http://dx.doi.org/10.1371/journal.pone.0235433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390403/
https://www.ncbi.nlm.nih.gov/pubmed/32726316
http://dx.doi.org/10.1371/journal.pone.0235433

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