Decreased Naïve T-cell Production Leading to Cytokine Storm as Cause of Increased COVID-19 Severity with Comorbidities

Aging, type 2 diabetes, and male gender are major risk factors leading to increased COVID-19 morbidity and mortality. Thymic production and the export of naïve T cells decrease with aging through the effects of androgens in males and in type 2 diabetes. Furthermore, with aging, recovery of naïve T-c...

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Detalles Bibliográficos
Autores principales: Schwartz, Michael D, Emerson, Stephen G, Punt, Jennifer, Goff, Willow D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390514/
https://www.ncbi.nlm.nih.gov/pubmed/32765940
http://dx.doi.org/10.14336/AD.2020.0619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390514/
https://www.ncbi.nlm.nih.gov/pubmed/32765940
http://dx.doi.org/10.14336/AD.2020.0619

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