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Decreased Naïve T-cell Production Leading to Cytokine Storm as Cause of Increased COVID-19 Severity with Comorbidities
Aging, type 2 diabetes, and male gender are major risk factors leading to increased COVID-19 morbidity and mortality. Thymic production and the export of naïve T cells decrease with aging through the effects of androgens in males and in type 2 diabetes. Furthermore, with aging, recovery of naïve T-c...
Autores principales: | Schwartz, Michael D, Emerson, Stephen G, Punt, Jennifer, Goff, Willow D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390514/ https://www.ncbi.nlm.nih.gov/pubmed/32765940 http://dx.doi.org/10.14336/AD.2020.0619 |
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