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DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation
DICER1 deficiency in the retinal pigment epithelium (RPE) was associated with the accumulation of Alu transcripts and implicated in geographic atrophy (GA), a form of age-related macular degeneration (AMD), an eye disease leading to blindness in millions of people. Although the exact mechanism of th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390522/ https://www.ncbi.nlm.nih.gov/pubmed/32765950 http://dx.doi.org/10.14336/AD.2019.0809 |