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DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation

DICER1 deficiency in the retinal pigment epithelium (RPE) was associated with the accumulation of Alu transcripts and implicated in geographic atrophy (GA), a form of age-related macular degeneration (AMD), an eye disease leading to blindness in millions of people. Although the exact mechanism of th...

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Detalles Bibliográficos
Autores principales:	Kaarniranta, Kai, Pawlowska, Elzbieta, Szczepanska, Joanna, Blasiak, Janusz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JKL International LLC 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390522/ https://www.ncbi.nlm.nih.gov/pubmed/32765950 http://dx.doi.org/10.14336/AD.2019.0809

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