Chromokinesin KIF4A teams up with stathmin 1 to regulate abscission in a SUMO-dependent manner

Cell division ends when two daughter cells physically separate via abscission, the cleavage of the intercellular bridge. It is not clear how the anti-parallel microtubule bundles bridging daughter cells are severed. Here, we present a novel abscission mechanism. We identified chromokinesin KIF4A, wh...

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Detalles Bibliográficos
Autores principales: Cuijpers, Sabine A. G., Willemstein, Edwin, Ruppert, Jan G., van Elsland, Daphne M., Earnshaw, William C., Vertegaal, Alfred C. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390632/
https://www.ncbi.nlm.nih.gov/pubmed/32591481
http://dx.doi.org/10.1242/jcs.248591

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