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A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors

Peptide therapeutics, unlike small-molecule drugs, display crucial advantages of target specificity and the ability to block large interacting interfaces, such as those of transcription factors. The transcription co-factor of the Hippo pathway, YAP/Yorkie (Yki), has been implicated in many cancers,...

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Detalles Bibliográficos
Autores principales: Bajpai, Anjali, Quazi, Taushif Ahmad, Tang, Hong-Wen, Manzar, Nishat, Singh, Virender, Thakur, Ashwani, Ateeq, Bushra, Perrimon, Norbert, Sinha, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390633/
https://www.ncbi.nlm.nih.gov/pubmed/32540914
http://dx.doi.org/10.1242/dmm.044420