H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory

Most eukaryotic centromeres are located within heterochromatic regions. Paradoxically, heterochromatin can also antagonize de novo centromere formation, and some centromeres lack it altogether. In order to investigate the importance of heterochromatin at centromeres, we used epigenetic engineering o...

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Detalles Bibliográficos
Autores principales: Martins, Nuno M. C., Cisneros-Soberanis, Fernanda, Pesenti, Elisa, Kochanova, Natalia Y., Shang, Wei-Hao, Hori, Tetsuya, Nagase, Takahiro, Kimura, Hiroshi, Larionov, Vladimir, Masumoto, Hiroshi, Fukagawa, Tatsuo, Earnshaw, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390644/
https://www.ncbi.nlm.nih.gov/pubmed/32576667
http://dx.doi.org/10.1242/jcs.242610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390644/
https://www.ncbi.nlm.nih.gov/pubmed/32576667
http://dx.doi.org/10.1242/jcs.242610

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