Genomic profiling of primary and recurrent adult granulosa cell tumors of the ovary

Adult-type granulosa cell tumor (aGCT) is a rare malignant ovarian sex cord-stromal tumor, harboring recurrent FOXL2 c.C402G/p.C134W hotspot mutations in 97% of cases. These tumors are considered to have a favorable prognosis, however aGCTs have a tendency for local spread and late recurrences, whic...

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Detalles Bibliográficos
Autores principales: Da Cruz Paula, Arnaud, da Silva, Edaise M., Segura, Sheila E., Pareja, Fresia, Bi, Rui, Selenica, Pier, Kim, Sarah H., Ferrando, Lorenzo, Vahdatinia, Mahsa, Soslow, Robert A., Vidal, August, Gatius, Sonia, Przybycin, Christopher G, Abu-Rustum, Nadeem R., Matias-Guiu, Xavier, Rubin, Brian P., Reis-Filho, Jorge S., DeLair, Deborah F., Weigelt, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390666/
https://www.ncbi.nlm.nih.gov/pubmed/32203090
http://dx.doi.org/10.1038/s41379-020-0514-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390666/
https://www.ncbi.nlm.nih.gov/pubmed/32203090
http://dx.doi.org/10.1038/s41379-020-0514-3

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