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Dual Electrocatalysis Enables Enantioselective Hydrocyanation of Conjugated Alkenes

Chiral nitriles and their derivatives are prevalent in pharmaceuticals and bioactive compounds. Enantioselective alkene hydrocyanation represents a convenient and efficient approach for synthesizing these molecules. However, a generally applicable method featuring a broad substrate scope and high fu...

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Detalles Bibliográficos
Autores principales: Song, Lu, Fu, Niankai, Ernst, Brian G., Lee, Wai Hang, Frederick, Michael O., DiStasio, Robert A., Lin, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390704/
https://www.ncbi.nlm.nih.gov/pubmed/32601407
http://dx.doi.org/10.1038/s41557-020-0469-5