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Efficient in Utero Gene Transfer to the Mammalian Inner Ears by the Synthetic Adeno-Associated Viral Vector Anc80L65

Sensorineural hearing loss is one of the most common sensory disorders worldwide. Recent advances in vector design have paved the way for investigations into the use of adeno-associated vectors (AAVs) for hearing disorder gene therapy. Numerous AAV serotypes have been discovered to be applicable to...

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Detalles Bibliográficos
Autores principales: Hu, Chin-Ju, Lu, Ying-Chang, Tsai, Yi-Hsiu, Cheng, Haw-Yuan, Takeda, Hiroki, Huang, Chun-Ying, Xiao, Ru, Hsu, Chuan-Jen, Tsai, Jin-Wu, Vandenberghe, Luk H., Wu, Chen-Chi, Cheng, Yen-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390729/
https://www.ncbi.nlm.nih.gov/pubmed/32775487
http://dx.doi.org/10.1016/j.omtm.2020.06.019