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Duloxetine hydrochloride loaded film forming dermal gel enriched with methylcobalamin and geranium oil attenuates paclitaxel-induced peripheral neuropathy in rats

OBJECTIVE: In attempt to conquer the major concerns of oral duloxetine hydrochloride (like low bioavailability, intolerable side-effects and no regeneration of demyelinated nerve fibres) for the management of chemotherapy-induced peripheral neuropathy (CIPN), an alternative delivery of duloxetine hy...

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Detalles Bibliográficos
Autores principales: Chahal, Simerjeet Kaur, Sodhi, Rupinder Kaur, Madan, Jitender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390834/
https://www.ncbi.nlm.nih.gov/pubmed/32760845
http://dx.doi.org/10.1016/j.ibror.2020.07.006