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Identification and Characterization of the Copy Number Dosage-Sensitive Genes in Colorectal Cancer

Dosage effect is one of the common mechanisms of somatic copy number alteration in the development of colorectal cancer, yet the roles of dosage-sensitive genes (DSGs) in colorectal cancer (CRC) remain to be characterized more deeply. In this study, we developed a five-step pipeline to identify DSGs...

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Detalles Bibliográficos
Autores principales: Chang, Zhiqiang, Liu, Xinxin, Zhao, Wenyuan, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390836/
https://www.ncbi.nlm.nih.gov/pubmed/32775488
http://dx.doi.org/10.1016/j.omtm.2020.06.020