Family-based exome sequencing identifies rare coding variants in age-related macular degeneration

Genome-wide association studies (GWAS) have identified 52 independent variants at 34 genetic loci that are associated with age-related macular degeneration (AMD), the most common cause of incurable vision loss in the elderly worldwide. However, causal genes at the majority of these loci remain unkno...

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Detalles Bibliográficos
Autores principales: Ratnapriya, Rinki, Acar, İlhan E, Geerlings, Maartje J, Branham, Kari, Kwong, Alan, Saksens, Nicole T M, Pauper, Marc, Corominas, Jordi, Kwicklis, Madeline, Zipprer, David, Starostik, Margaret R, Othman, Mohammad, Yashar, Beverly, Abecasis, Goncalo R, Chew, Emily Y, Ferrington, Deborah A, Hoyng, Carel B, Swaroop, Anand, den Hollander, Anneke I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390936/
https://www.ncbi.nlm.nih.gov/pubmed/32246154
http://dx.doi.org/10.1093/hmg/ddaa057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390936/
https://www.ncbi.nlm.nih.gov/pubmed/32246154
http://dx.doi.org/10.1093/hmg/ddaa057

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