ThETA: transcriptome-driven efficacy estimates for gene-based TArget discovery

SUMMARY: Estimating efficacy of gene–target-disease associations is a fundamental step in drug discovery. An important data source for this laborious task is RNA expression, which can provide gene–disease associations on the basis of expression fold change and statistical significance. However, the...

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Detalles Bibliográficos
Autores principales: Failli, Mario, Paananen, Jussi, Fortino, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390989/
https://www.ncbi.nlm.nih.gov/pubmed/32437556
http://dx.doi.org/10.1093/bioinformatics/btaa518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390989/
https://www.ncbi.nlm.nih.gov/pubmed/32437556
http://dx.doi.org/10.1093/bioinformatics/btaa518

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