Egr2 and 3 control inflammation, but maintain homeostasis, of PD-1(high) memory phenotype CD4 T cells

The transcription factors Egr2 and 3 are essential for controlling inflammatory autoimmune responses of memory phenotype (MP) CD4 T cells. However, the mechanism is still unclear. We have now found that the Egr2(+) subset (PD-1(high) MP) of MP CD4 T cells expresses high levels of checkpoint molecule...

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Detalles Bibliográficos
Autores principales: Symonds, Alistair LJ, Zheng, Wei, Miao, Tizong, Wang, Haiyu, Wang, TieShang, Kiome, Ruth, Hou, Xiujuan, Li, Suling, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391068/
https://www.ncbi.nlm.nih.gov/pubmed/32709717
http://dx.doi.org/10.26508/lsa.202000766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391068/
https://www.ncbi.nlm.nih.gov/pubmed/32709717
http://dx.doi.org/10.26508/lsa.202000766

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