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Egr2 and 3 control inflammation, but maintain homeostasis, of PD-1(high) memory phenotype CD4 T cells
The transcription factors Egr2 and 3 are essential for controlling inflammatory autoimmune responses of memory phenotype (MP) CD4 T cells. However, the mechanism is still unclear. We have now found that the Egr2(+) subset (PD-1(high) MP) of MP CD4 T cells expresses high levels of checkpoint molecule...
Autores principales: | Symonds, Alistair LJ, Zheng, Wei, Miao, Tizong, Wang, Haiyu, Wang, TieShang, Kiome, Ruth, Hou, Xiujuan, Li, Suling, Wang, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391068/ https://www.ncbi.nlm.nih.gov/pubmed/32709717 http://dx.doi.org/10.26508/lsa.202000766 |
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