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Inhibition of miR-17~92 Cluster Ameliorates High Glucose-Induced Podocyte Damage

The loss and damage of podocytes is an early feature of diabetic nephropathy (DN). The miR-17∼92 cluster was dysregulated in diabetic and polycystic kidney disease patients, but its role in DN is unclear. Hence, an in vitro study on the high glucose- (HG-) treated mouse podocytes (MPC5) was designed...

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Detalles Bibliográficos
Autores principales: Fan, Xiaobao, Hao, Zhiming, Li, Zhenjiang, Wang, Xiaoming, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391105/
https://www.ncbi.nlm.nih.gov/pubmed/32774146
http://dx.doi.org/10.1155/2020/6126490