Combinational inhibition of EGFR and YAP reverses 5-Fu resistance in colorectal cancer

Yes-associated protein (YAP) is a transcriptional coactivator that promotes cell proliferation, migration, and tissue homeostasis in colorectal cancer (CRC). Here, we established 5-Fu resistant CRC cell line (SW620R) and examined the role of YAP in chemotherapy resistance. We showed that YAP promote...

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Detalles Bibliográficos
Autores principales: Huang, Changhao, Chen, Zihua, Yang, Chen, Chen, Lu, Lai, Chen, Zhang, Yingying, Yuan, Weijie, Jeong, Ji-Hak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391200/
https://www.ncbi.nlm.nih.gov/pubmed/32742490
http://dx.doi.org/10.7150/jca.44775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391200/
https://www.ncbi.nlm.nih.gov/pubmed/32742490
http://dx.doi.org/10.7150/jca.44775

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