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Mitochondria-Associated Degradation Pathway (MAD) Function beyond the Outer Membrane

The mitochondria-associated degradation pathway (MAD) mediates ubiquitination and degradation of mitochondrial outer membrane (MOM) proteins by the proteasome. We find that the MAD, but not other quality-control pathways including macroautophagy, mitophagy, or mitochondrial chaperones and proteases,...

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Detalles Bibliográficos
Autores principales: Liao, Pin-Chao, Alessi Wolken, Dana M., Serrano, Edith, Srivastava, Pallavi, Pon, Liza A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391283/
https://www.ncbi.nlm.nih.gov/pubmed/32668258
http://dx.doi.org/10.1016/j.celrep.2020.107902