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Mitochondria-Associated Degradation Pathway (MAD) Function beyond the Outer Membrane
The mitochondria-associated degradation pathway (MAD) mediates ubiquitination and degradation of mitochondrial outer membrane (MOM) proteins by the proteasome. We find that the MAD, but not other quality-control pathways including macroautophagy, mitophagy, or mitochondrial chaperones and proteases,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391283/ https://www.ncbi.nlm.nih.gov/pubmed/32668258 http://dx.doi.org/10.1016/j.celrep.2020.107902 |