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Role of tumor suppressor molecules in genomic perturbations and damaged DNA repair involved in the pathogenesis of cancer and neurodegeneration (Review)

Genomic perturbations due to inaccurate DNA replication, including inappropriate chromosomal segregation often underlie the development of cancer and neurodegenerative diseases. The incidence of these two diseases increases with age and exhibits an inverse association. Therefore, elderly subjects wi...

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Detalles Bibliográficos
Autores principales: Matsuda, Satoru, Murakami, Mutsumi, Ikeda, Yuka, Nakagawa, Yukie, Tsuji, Ai, Kitagishi, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391300/
https://www.ncbi.nlm.nih.gov/pubmed/32765849
http://dx.doi.org/10.3892/br.2020.1317