Exocytosis of large-diameter lysosomes mediates interferon γ-induced relocation of MHC class II molecules toward the surface of astrocytes

Astrocytes are the key homeostatic cells in the central nervous system; initiation of reactive astrogliosis contributes to neuroinflammation. Pro-inflammatory cytokine interferon γ (IFNγ) induces the expression of the major histocompatibility complex class II (MHCII) molecules, involved in antigen p...

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Detalles Bibliográficos
Autores principales: Božić, Mićo, Verkhratsky, Alexei, Zorec, Robert, Stenovec, Matjaž
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391398/
https://www.ncbi.nlm.nih.gov/pubmed/31667557
http://dx.doi.org/10.1007/s00018-019-03350-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391398/
https://www.ncbi.nlm.nih.gov/pubmed/31667557
http://dx.doi.org/10.1007/s00018-019-03350-8

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