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Partial Activation of TrkB Receptors Corrects Interneuronal Calcium Channel Dysfunction and Reduces Epileptogenic Activity in Neocortex following Injury
Decreased GABAergic inhibition due to dysfunction of inhibitory interneurons plays an important role in post-traumatic epileptogenesis. Reduced N-current Ca(2+) channel function in GABAergic terminals contributes to interneuronal abnormalities and neural circuit hyperexcitability in the partial neoc...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391412/ https://www.ncbi.nlm.nih.gov/pubmed/32488246 http://dx.doi.org/10.1093/cercor/bhz254 |