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Questioning the IGF1 receptor’s assigned role in CRC – a case for rehabilitation?

BACKGROUND: The insulin-like growth factor 1 receptor (IGF1R) is suspected to be involved in colorectal carcinogenesis and has been associated with worse survival in colorectal cancer (CRC). We hypothesized that the alleged suspect might be in truth beyond any suspicion. We investigated if the expre...

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Detalles Bibliográficos
Autores principales: Heckl, Steffen M., Pellinghaus, Marie, Behrens, Hans-Michael, Krüger, Sandra, Schreiber, Stefan, Röcken, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391533/
https://www.ncbi.nlm.nih.gov/pubmed/32727431
http://dx.doi.org/10.1186/s12885-020-07173-w